RE: Proteinuria 42 minutes ago

Thank you very much for your advice. ------------------------------ Soroush Shojai MD Associate Professor University of Alberta Edmonton AB 0044...

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RE: Proteinuria 44 minutes ago

Thank you for your advice. We haven't repeated her US recently but her kidney was 9.5 Cm on the latest US. I am not aware of her birth eight but ...

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RE: Proteinuria 50 minutes ago

The other symptoms reported are consistent with zoledronic acid induced systemic inflammation, a well reported phenomenon, and I wouldn't necessari...

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RE: Proteinuria 1 hour ago

Yes her serum Albumin is normal and she doesn't have any oedema. Thank you very much for your advice. ------------------------------ Soroush S...

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RE: Proteinuria 1 hour ago

Thank you for your advice. I agree ATIN is a possibility and it was discussed among our team. However, the consensus was even if the biopsy shows A...

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RE: Proteinuria 1 hour ago

Hi Thank you for your reply. She doesn't have any glycosuria. ------------------------------ Soroush Shojai MD Associate Professor University ...

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RE: Proteinuria 1 hour ago

Reviewed labs - could follow for now on present meds- reserve biopsy if eGFR decreases or becomes nephrotic ( serum albumin normal if read table co...

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RE: Urine Sodium In Hyponatremia 1 hour ago

I completely agree with Dr. R. Rodby. This is not salt wasting nephropathy, but typical SIADH. Hence the use of the 2 % saline just allowed the ser...

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RE: MCD-IgA nephropathy 1 hour ago

Ok- good luck keep us informed ! ------------------------------ [Mark] [Lerman] [MD,FASN,FACP,FAST] AST KPCOP EC [Past Medical Director Kidney Pa...

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RE: Are International Kidney Disease Guidelines Equally Applicable Across Different Healthcare Settings? 3 hours ago

I do not have any good answers to your questions. guideline writers try to take into account the global heterogeneity of availability of drugs to t...

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RE: finerinoneh 3 hours ago

I can't find any published information that answers your question. We will gave to rely on the opinion of someone who has experience with treating ...

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RE: MCD-IgA nephropathy 5 hours ago

He's been on it for a while, I stopped it during this last visit. I am planning to start tapering steroids by next 2 weeks. He does have some ste...

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RE: MCD-IgA nephropathy 5 hours ago

"He takes hydralazine, hydrochlorothiazide, bumex and metformin." suspect rash not steroids but agree with referred to dermatology for possible s...

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RE: Proteinuria 6 hours ago

Pamidronate is associated with FSGS while zolindronte is associated with ATI. Solitary kidney is not an absolute CI for kidney biopsy so I would pr...

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RE: Proteinuria 8 hours ago

any glucosuria present on UA ? --------------------------------- Edgard Wehbe MD, FASN Wichita Nephrology Group Wichita KS (316) 993-6580 ----...

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RE: Lupus nephritis - Renal Limited TMA - Complement mediated CAPS 9 hours ago

Agree with Dr. Glassock and i think all lesions can be explained by LN even the TMA so my plan to wait for OBI plus SOC (MMF and PRD) to work befor...

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RE: Lupus nephritis - Renal Limited TMA - Complement mediated CAPS 10 hours ago

Thanks It is a complicated case of a patient presenting with 2 major thrombotic events . His biopsy shows class 4 lupus Nephritis There is a sug...

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RE: Proteinuria 12 hours ago

What is the size of the solitary Kidney by US ? Do you happen to kniw her birth weight?. What is her systolic BP and ABOM (nocturnal dipping) ?. Wh...

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RE: Lupus nephritis - Renal Limited TMA - Complement mediated CAPS 12 hours ago

Dr-Dastoor- Given the findings in this complex case of LN, I have difficulty understanding the rationale for using anti -C5 MoAb -can you succinc...

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RE: Lupus nephritis - Renal Limited TMA - Complement mediated CAPS 13 hours ago

Genetic testing done Obi given last night Eculizimab planned for tomorrow, Ravulizumab as an outpatient --------------------------------- Dr. Ho...

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RE: are foamy cells in kidney biopsy synonymous with fabry disease? 15 hours ago

I would do genetic studies for Alport and Fabry Disease on potential donor and intended recipient in this case. Interstitial foam cels are abnormal...

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Proteinuria 16 hours ago

I would like to ask my colleagues' opinion on this patient. 61 years old female with solitary kidney ( Donated her kidney 12 years ago), presente...

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RE: MCD-IgA nephropathy 16 hours ago

he does have microscopic hematuria, persistently 17-26 RBCs on UA. ------------------------------ Sarah Al Zoubi MD John Stroger Hospital of Cook...

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RE: MCD-IgA nephropathy 16 hours ago

He takes hydralazine, hydrochlorothiazide, bumex and metformin. I think it is more drug eruption from steroids. he was referred to dermatology fo...

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RE: Urine Sodium In Hyponatremia 16 hours ago

On 28th October his Pna was 118 . He was placed on 2% saline for 24 hours . His Una was 160 and Uosm was 550 while on 2% saline . On 29th October ...

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RE: Urine Sodium In Hyponatremia 17 hours ago

"His serum creatinine is 28 umol/l or 0.4 mg/dl, urea is 4 mmol/l ( 12 mg/dl) uric acid 72 umol/L" Dr. Dastoor: Were these the presenting values be...

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RE: are foamy cells in kidney biopsy synonymous with fabry disease? 17 hours ago

should i check for Fabry disease? ------------------------------ Muhammad Soobadar MBChB UK ------------------------------

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are foamy cells in kidney biopsy synonymous with fabry disease? 17 hours ago

59 F coming foward to be considered as live donor for nephew PMH: 3 previous C sections - one under GA and 2 under spinal : Nil issues Frozen ...

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RE: Urine Sodium In Hyponatremia 18 hours ago

exactly why a measured urine sodium assuming no diuretics for several days would have been informative ------------------------------ [Mark] [Ler...

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RE: Urine Sodium In Hyponatremia 21 hours ago

I attached the aforementioned article about the value of the Una over the physical exam for euvolemia v hypovolemia in HypoNa. TO me this is a clas...

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RE: Urine Sodium In Hyponatremia 21 hours ago

Was urine sodium measured when pNA was 118? ------------------------------ [Mark] [Lerman] [MD,FASN,FACP,FAST] AST KPCOP EC [Past Medical Directo...

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RE: Urine Sodium In Hyponatremia 1 day ago

Please see attachment . On 28th October :patient on 2% Ncal , which has 308 osmoles of Na - Uosm is 160 On 29th October : patient is 10 hours of...

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RE: Urine Sodium In Hyponatremia 1 day ago

The calculation is made from the original patient's U Na of 160 and U osm of 585. Assuming the Na content of the excreted urine is unchanged a U ...

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RE: Lupus nephritis - Renal Limited TMA - Complement mediated CAPS 1 day ago

This is aggressive course of active lupus for sure based on clinical serollogical and histopathology but yes i would agree wigh dr dustoor to rule ...

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RE: Urine Sodium In Hyponatremia 1 day ago

"if the U osm was 118 the U Na would be 32 mmol/L" -how was this calculated without measuring spot urine sodium? ------------------------------ [...

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RE: MCD-IgA nephropathy 1 day ago

interesting-why with favorable response so far to steroids and no evidence at least posted of significant steroid toxicity-why switch to RTX which ...

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RE: Urine Sodium In Hyponatremia 1 day ago

If the U osm was 118 the U Na would be 32 mmol/L. This suggests euvolemia but may overlap with modest hypovolemia. Under the influence of ADH the N...

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RE: Urine Sodium In Hyponatremia 1 day ago

https://pmc.ncbi.nlm.nih.gov/articles/PMC12332142/ This addresses the question of the post, which I believe asks whether the kidney that perceive...

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RE: Urine Sodium In Hyponatremia 1 day ago

Very interesting presentation. While several diseases can present with hyponatremia and salt wasting, the most important one is cerebral salt wasti...

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RE: Urine Sodium In Hyponatremia 1 day ago

I find the above signs - turgor / sunken eyeballs not particularly reliable measures of volume status vs JVP and edema. Perhaps measuring fractiona...

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finerinoneh 1 day ago

Good evening For patients with stable GFR around 20mls/min and K [More]

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RE: Urine Sodium In Hyponatremia 1 day ago

Interesting case. It certainly sounds like the kidneys are not sensing a hypovolemic state or decreased effective circulating volume, even if he is...

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RE: Urine Sodium In Hyponatremia 1 day ago

I think you have to trust the kidneys assessment of effective circulating volume. He may appear volume depleted (i prefer this terminology over deh...

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RE: Lupus nephritis - Renal Limited TMA - Complement mediated CAPS 1 day ago

I agree , but our rheumatologist is highly suspicious of antibody negative APLS and there are fibrin thrombi in the kidney biopsy which may be sugg...

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Urine Sodium In Hyponatremia 1 day ago

Was reviewing a patient with hyponatremia and Pna 118 on admission . It was felt that he was dehydrated and was started on 2% Nacl , not 0.9% Nacl....

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RE: MCD-IgA nephropathy 1 day ago

To develop a new leucocytoclastic cutaneous Vasculitis due to IgAV ipwhile on high dose steroids - is highly improbable. ivwoukd continue with RTX ...

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RE: MCD-IgA nephropathy 1 day ago

does not look like typical rash from steroids? what other meds is patient taking? good response ( decrease proteinuria) so far FROM AI The typi...

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RE: Drug-induced lupus and ANCA GN 1 day ago

My answer to this question is NO! There are plenty of non-hydralazine agents that can be used for BP control. Why take the rusk? ----------------...

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RE: Lupus nephritis - Renal Limited TMA - Complement mediated CAPS 2 days ago

Why not the whole picture is just LN without systemic thromboembolic events as SLE can present with thrombosis events independent of APS. Agree fo...

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RE: Drug-induced lupus and ANCA GN 2 days ago

Is it safe to use hydralazine in patients with MPO MPA Anca vasculitis ? The reason I ask, is that we have a patient in the ICU, with severe MPO v...

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